Semax
Semax is an artificial heptapeptide based on ACTH(4-10). This substance is used in studies related to BDNF upregulation, neuroprotection, and cognitive research in laboratories. The creation of Semax was initiated at the Institute of Molecular Genetics, Russian Academy of Sciences.
About Semax
Semax (Met-Glu-His-Phe-Pro-Gly-Pro) is a man-made compound of the ACTH(4-7) fragment with a Pro-Gly-Pro addition enhancing metabolic stability. Semax has attracted significant attention in Russian neuropharmacological studies and is now gaining increasing recognition worldwide.
Studies on Semax include investigations related to the up-regulation of BDNF and NGF activity, the regulation of dopaminergic and serotonergic systems, as well as neuroprotective properties.
Research Areas
- BDNF and NGF upregulation studies in neuronal cell cultures
- Neuroprotection research in ischaemia and hypoxia laboratory models
- Dopaminergic and serotonergic receptor system investigations
- ACTH receptor pathway research and cognitive function studies
- Stroke recovery and brain plasticity research in animal models
- Attention, memory, and learning pathway investigations in vitro
⚠ Research Use Only.
All products supplied by PeptidesX are intended strictly for in-vitro laboratory and scientific research. Not for human consumption, medical use, veterinary use, or therapeutic application. Researchers are responsible for compliance with all applicable regulations in their jurisdiction.
Identity & Purity
HPLC / MS-UPLC| Test | Specification | Result |
| Appearance | White lyophilised powder | ✓ Conforms |
| HPLC Purity | ≥ 98.0% | 99.2% ✓ |
| MS Molecular Weight | Expected ± 0.5 Da | Confirmed ✓ |
| Amino Acid Analysis | Theoretical sequence | Confirmed ✓ |
| Water Content (KF) | ≤ 8.0% | 5.4% ✓ |
| Net Peptide Content | ≥ 85.0% | 90.8% ✓ |
Safety Testing
Endotoxin / Metals| Test | Specification | Result |
| Endotoxin (LAL) | ≤ 5 EU/mg | 0.9 EU/mg ✓ |
| Bioburden | ≤ 100 CFU/g | <10 CFU/g ✓ |
| Lead (Pb) | ≤ 10 ppm | <0.1 ppm ✓ |
| Arsenic (As) | ≤ 5 ppm | <0.1 ppm ✓ |
| Mercury (Hg) | ≤ 3 ppm | <0.1 ppm ✓ |
| Cadmium (Cd) | ≤ 5 ppm | <0.1 ppm ✓ |
Solubility: Water. Mix gently by rolling — do not vortex.
Returns: Sealed, unopened vials may be returned within 14 days of receipt. Opened vials cannot be returned.
Semax is a synthetic peptide originally developed for neuroscience research. It has gained significant scientific interest due to its potential effects on cognitive function, neuroprotection, learning processes, memory formation, and brain-derived neurotrophic factor (BDNF) pathways.
Semax is commonly referred to simply as Semax Peptide in scientific literature. It is a modified peptide derived from adrenocorticotropic hormone (ACTH) fragments and is widely studied in neurological research.
Semax has attracted attention because of its unique relationship with cognitive and neurological pathways. Researchers continue to investigate its effects on memory, focus, learning, mental performance, and neuroplasticity.
Researchers believe Semax may influence neurotransmitter systems and neurotrophic factors involved in brain function. Studies have examined its interaction with pathways related to cognition, neuroprotection, and neuronal communication.
Current research areas include:
. Cognitive performance studies
. Memory and learning research
. Neuroprotection investigations
. Focus and attention research
. Brain-derived neurotrophic factor (BDNF) studies
. Neuroplasticity research
. Mental performance investigations
. Healthy ageing and brain health research
Published studies have explored Semax's potential effects on memory formation, cognitive performance, learning processes, and neuroprotective mechanisms. Ongoing research continues to investigate its biological activity and neurological significance.
Yes. Memory and learning are among the most common areas of Semax research. Scientists continue to investigate how the peptide may influence information processing, retention, and cognitive adaptation.
Researchers frequently study Semax in relation to attention, concentration, and cognitive efficiency. Its potential effects on neurological signalling pathways remain an active area of investigation.
Semax is often discussed within nootropic and cognitive enhancement research because of its association with learning, memory, and brain function studies. Researchers continue to evaluate its mechanisms and applications.
Research-grade Semax is available through specialist peptide suppliers serving the UK research community. Availability may vary depending on supplier inventory and product format.
Researchers should purchase Semax from reputable suppliers that provide batch-specific Certificates of Analysis, purity testing results, and transparent quality assurance procedures.
Yes. Research-grade Semax is available from selected peptide suppliers online. Researchers should verify analytical testing, supplier reputation, and quality control documentation before purchasing.
Semax is commonly supplied as a lyophilised peptide powder in various vial strengths. Available concentrations may differ depending on supplier offerings.
Premium research-grade Semax is typically verified through HPLC and mass spectrometry testing. Batch-specific purity information is generally provided through a Certificate of Analysis.
Semax is commonly supplied as a lyophilised peptide powder and is reconstituted using suitable laboratory-grade diluents. Researchers should follow established laboratory protocols and handling procedures.
Lyophilised Semax should be stored according to the supplier's recommendations. Proper storage conditions help maintain peptide stability and research integrity.
Researchers should look for:
. Batch-specific Certificates of Analysis
. HPLC purity verification
. Mass spectrometry testing
. Transparent quality control standards
. Reliable UK delivery
. Consistent product availability
Semax has built a strong scientific reputation due to decades of neurological research investigating memory, learning, neuroprotection, and cognitive performance. Its unique relationship with brain function continues to make it one of the most studied peptides in neuroscience research.