Semax
Semax is an artificial heptapeptide based on ACTH(4-10). This substance is used in studies related to BDNF upregulation, neuroprotection, and cognitive research in laboratories. The creation of Semax was initiated at the Institute of Molecular Genetics, Russian Academy of Sciences.
About Semax
Semax (Met-Glu-His-Phe-Pro-Gly-Pro) is a man-made compound of the ACTH(4-7) fragment with a Pro-Gly-Pro addition enhancing metabolic stability. Semax has attracted significant attention in Russian neuropharmacological studies and is now gaining increasing recognition worldwide.
Studies on Semax include investigations related to the up-regulation of BDNF and NGF activity, the regulation of dopaminergic and serotonergic systems, as well as neuroprotective properties.
Research Areas
- BDNF and NGF upregulation studies in neuronal cell cultures
- Neuroprotection research in ischaemia and hypoxia laboratory models
- Dopaminergic and serotonergic receptor system investigations
- ACTH receptor pathway research and cognitive function studies
- Stroke recovery and brain plasticity research in animal models
- Attention, memory, and learning pathway investigations in vitro
⚠ Research Use Only.
All products supplied by PeptidesX are intended strictly for in-vitro laboratory and scientific research. Not for human consumption, medical use, veterinary use, or therapeutic application. Researchers are responsible for compliance with all applicable regulations in their jurisdiction.
Identity & Purity
HPLC / MS-UPLC| Test | Specification | Result |
| Appearance | White lyophilised powder | ✓ Conforms |
| HPLC Purity | ≥ 98.0% | 99.2% ✓ |
| MS Molecular Weight | Expected ± 0.5 Da | Confirmed ✓ |
| Amino Acid Analysis | Theoretical sequence | Confirmed ✓ |
| Water Content (KF) | ≤ 8.0% | 5.4% ✓ |
| Net Peptide Content | ≥ 85.0% | 90.8% ✓ |
Safety Testing
Endotoxin / Metals| Test | Specification | Result |
| Endotoxin (LAL) | ≤ 5 EU/mg | 0.9 EU/mg ✓ |
| Bioburden | ≤ 100 CFU/g | <10 CFU/g ✓ |
| Lead (Pb) | ≤ 10 ppm | <0.1 ppm ✓ |
| Arsenic (As) | ≤ 5 ppm | <0.1 ppm ✓ |
| Mercury (Hg) | ≤ 3 ppm | <0.1 ppm ✓ |
| Cadmium (Cd) | ≤ 5 ppm | <0.1 ppm ✓ |
Solubility: Water. Mix gently by rolling — do not vortex.
Returns: Sealed, unopened vials may be returned within 14 days of receipt. Opened vials cannot be returned.
Semax is available for purchase in the UK solely for scientific research and testing applications. PeptidesX provides all products for use in scientific research only, in accordance with UK laws. It is not for human consumption.
Every package will include the following: the lyophilized peptide vial, a certificate of analysis for your order (confirmed by HPLC and MS), a research use statement, and cold shipping.
Orders made before 3PM from Monday to Friday will be dispatched on the same day through the use of the service called "Royal Mail Tracked 24." A tracking number will be sent to you through email. Typically, orders within the UK are delivered on the following working day.
Yes, volume discount is available for laboratories, universities, and any other regular research clients. Get in touch with us about your specific needs and we can prepare an estimate for you.
Each batch is subjected to an independent analysis conducted by an accredited third-party lab using HPLC and MS-UPLC. We do not self-certify batches – we only send you a certificate that relates specifically to your batch.