PT-141
PT-141, also referred to as Bremelanotide, is an artificial peptide analogue from the melanocortin peptides. The drug is mainly evaluated due to its ability to affect the action of the melanocortin receptors, especially MC3R and MC4R, which are essential in signaling, neuroendocrine function and behavioral physiology. Differently from other drugs with primary action through the […]
PT-141, also referred to as Bremelanotide, is an artificial peptide analogue from the melanocortin peptides. The drug is mainly evaluated due to its ability to affect the action of the melanocortin receptors, especially MC3R and MC4R, which are essential in signaling, neuroendocrine function and behavioral physiology. Differently from other drugs with primary action through the vasculature, PT-141 is used in laboratory experiments due to its effect on central melanocortin signaling.
The use of PT-141 in preclinical and laboratory studies includes the investigation of activation of the melanocortin receptors, neuroendocrine signaling, physiology of reproduction, hypothalamic function, neurotransmitters, behavioral neuroscience and peptide receptor pharmacology. Studies were performed to evaluate the role of the melanocortin pathway in the regulation of behavior, appetite, autonomic nervous system and central nervous system signaling. However, the majority of the research about the mechanisms of action of PT-141 is experimental.
Unlike medicinal drugs, PT-141 provided by PeptidesX is meant for lab testing, analysis, and pre-clinical research purposes only. It is not approved for human or animal use by PeptidesX. Every batch of this product comes with the Certificate of Analysis detailing information on identity, purity, and analytical data for that particular batch. Researchers should always check the Certificate of Analysis provided with the product before conducting any tests.
All PT-141 products provided by PeptidesX are meant for research purposes only.
Research Areas
- Melanocortin receptors (MC3R and MC4R) studies
- Neuroendocrine signaling studies
- Hypothalamus pathways studies
- Studies on reproductive physiology
- Studies on behavioral neuroscience
- Studies on central nervous system signaling
- Studies on peptide receptor pharmacology
- Appetite regulation and autonomic nervous system studies
⚠ Research Use Only.
All products supplied by PeptidesX are intended strictly for in-vitro laboratory and scientific research. Not for human consumption, medical use, veterinary use, or therapeutic application. Researchers are responsible for compliance with all applicable regulations in their jurisdiction.
Identity & Purity
HPLC / MS-UPLC| Test | Specification | Result |
| Appearance | White lyophilised powder | ✓ Conforms |
| HPLC Purity | ≥ 98.0% | 99.% ✓ |
| MS Molecular Weight | Expected ± 0.5 Da | Confirmed ✓ |
| Amino Acid Analysis | Theoretical sequence | Confirmed ✓ |
| Water Content (KF) | ≤ 8.0% | 5.4% ✓ |
| Net Peptide Content | ≥ 85.0% | 90.8% ✓ |
Safety Testing
Endotoxin / Metals| Test | Specification | Result |
| Endotoxin (LAL) | ≤ 5 EU/mg | 0.9 EU/mg ✓ |
| Bioburden | ≤ 100 CFU/g | <10 CFU/g ✓ |
| Lead (Pb) | ≤ 10 ppm | <0.1 ppm ✓ |
| Arsenic (As) | ≤ 5 ppm | <0.1 ppm ✓ |
| Mercury (Hg) | ≤ 3 ppm | <0.1 ppm ✓ |
| Cadmium (Cd) | ≤ 5 ppm | <0.1 ppm ✓ |
Solubility: Water / Acetic acid. Mix gently by rolling — do not vortex.
Returns: Sealed, unopened vials may be returned within 14 days of receipt. Opened vials cannot be returned.
PT-141, also referred to as Bremelanotide, is a synthetic peptide analogue that has been developed for use in laboratory studies to explore melanocortin receptor signalling and neuroendocrine physiology.
Laboratory scientists examine PT-141 in their research studies due to its ability to activate MC3R and MC4R melanocortin receptors. This allows exploring signalling and biological pathways in the central nervous system.
Yes. PT-141 may be bought from PeptidesX for research purposes in the UK only. The peptide is available solely for scientific investigations and not intended for human or veterinary use.
Choose your preferred PT-141 product from the PeptidesX website and place your order online. The peptide is available strictly under the research-use-only policy of the manufacturer.
All products undergo independent analysis and have batch-specific documentation. The researcher should examine the Certificate of Analysis for information on the identity and purity of each batch.
The researchers explore PT-141 to improve their knowledge about receptor activation, neuroendocrine signalling, hypothalamus physiology, reproductive physiology, behavioural physiology, etc.
The study involves the use of laboratory animals in the study of melanocortin receptor pharmacology, neurotransmission, hypothalamic control, reproduction physiology, behavioral neuroscience, feeding control, and autonomic nervous system activity.
PT-141 comes in lyophilized form for research in laboratory experiments. Product details, purity and other information are available at the product's webpage.
It is advisable that researchers abide by the recommendations contained on the product's label and certificate of analysis. Laboratory products are to be stored under appropriate conditions away from excessive heat, humidity, direct sunlight, and frequent changes in temperatures.
Yes. Preclinical studies have been done on the PT-141 as a melanocortin receptor agonist in order to explore the understanding of receptor activation, neuroendocrine regulation and central nervous system signaling. The research has only been done in the laboratory setting and does not constitute proof of safety or efficacy in humans.
Yes. PT-141 is used by researchers in experiments related to melanocortin, reproduction physiology, behavioral neuroscience, neuroendocrine signaling, and peptide receptor pharmacology.
No. PT-141 supplied by PeptidesX is an investigational research peptide that can be used solely for laboratory experiments. It is not available as a drug or supplement.
Not at all. PeptidesX sells PT-141 only for laboratory study purposes. Data collected from laboratory and animal experiments cannot prove the safety, efficiency, and applicability of the product to humans; thus, PT-141 must not be used for personal or veterinarian needs.
Delivery choices for UK-based clients are available at the checkout process. The shipping method, delivery times, and cost are available on our website prior to ordering
PT-141 is designed for universities, research labs, biotech organizations, and scientists who are conducting proper scientific studies.