Melanotan-2
Melanotan-2 is a synthetic research peptide studied in laboratory settings for its interactions with melanocortin receptors, melanogenesis, pigmentation pathways, and melanin production. Supplied with batch-specific Certificate of Analysis documentation for scientific research use only.
About Melanotan-2
Melanotan-2 (MT-2) is an artificial analog of naturally occurring alpha-melanocyte-stimulating hormone (α-MSH). This peptide has become popular among researchers because of its interactions with melanocortin receptors, a class of receptors responsible for such processes as pigmentation, energy metabolism, inflammation, and neuroendocrine signaling. Melanotan-2 is used by researchers in laboratory conditions for gaining deeper insight into the mechanisms of melanocortin receptor functioning and related biological processes.
Scientific studies that involved Melanotan-2 included the study of melanogenesis, melanin synthesis, activation of melanocortin receptors, appetite control, and neuroendocrine signaling. In addition, preclinical studies of receptor selectivity and physiological effects of Melanotan-2 mediated by melanocortin system were performed. However, despite continued research on Melanotan-2, this compound stays investigational and should be used exclusively for laboratory and scientific research.
Each batch may be accompanied by the Certificate of Analysis that contains pertinent information about the identity and purity of the product and batch testing results.
All Melanotan-2 peptides supplied by PeptidesX are intended exclusively for laboratory research use and cannot be used for human or veterinary purposes.
Research Areas
- Melanocortin receptor signaling studies
- Melanogenesis and pigment biology studies
- Alpha-MSH analogs pathway studies
- Neuroendocrine signaling studies
- Appetite and energy balance pathway studies
- Receptor pharmacology and ligand binding studies
- Cellular signaling and peptide receptors biology studies
Melanotan-2 in Pigmentation Research
Melanotan-2 provides a research model for investigating melanocortin receptor signalling and its relationship with pigmentation biology. Laboratory studies may examine receptor interactions, melanogenesis, melanin-associated pathways and downstream cellular responses under controlled experimental conditions.
For reproducible research, material identity, purity and batch traceability are important considerations. Melanotan-2 supplied by PeptidesX is designated strictly for research use only (RUO). Batch-specific Certificate of Analysis (COA) documentation provides relevant analytical information for researchers evaluating the material. PeptidesX also provides educational resources covering HPLC and LC-MS testing, peptide purity and COA interpretation to support informed research-material assessment. Not for human or veterinary use.
Scientific References
- Dorr RT, et al. – Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study. Early controlled human research evaluating Melanotan-II, including pigmentation effects and reported physiological effects.pubmed.ncbi.nlm.nih.gov ↗
- Wessells H, et al. – Synthetic melanotropic peptide initiates erections in men with psychogenic erectile dysfunction: double-blind, placebo controlled crossover study. Journal of Urology, 1998. A placebo-controlled human study investigating the physiological effects of Melanotan-II.pubmed.ncbi.nlm.nih.gov ↗
- Wessells H, et al. – Effect of an alpha-melanocyte stimulating hormone analog on penile erection and sexual desire in men with organic erectile dysfunction. Urology, 2000. Randomised, double-blind, placebo-controlled crossover research examining MT-II in human subjects.pubmed.ncbi.nlm.nih.gov ↗
- Wessells H, et al. – Melanocortin receptor agonists, penile erection, and sexual motivation: human studies with Melanotan II. International Journal of Impotence Research, 2000. Reviews human research on MT-II as a melanocortin receptor agonist and reports findings from subjects with erectile dysfunction.pubmed.ncbi.nlm.nih.gov ↗
- Habbema L, et al. – Risks of unregulated use of alpha-melanocyte-stimulating hormone analogues: a review. International Journal of Dermatology, 2017. Useful for balancing a research page because it reviews safety concerns surrounding unregulated Melanotan I and II use.pubmed.ncbi.nlm.nih.gov ↗
- UK MHRA – Melanotan II products and suspected adverse drug reactions. For UK-specific regulatory context, the MHRA states that unauthorised Melanotan-II products do not have established safeguards demonstrating quality, safety or effectiveness and provides information on UK Yellow Card reports.assets.publishing.service.gov.uk ↗
⚠ Research Use Only.
All products supplied by PeptidesX are intended strictly for in-vitro laboratory and scientific research. Not for human consumption, medical use, veterinary use, or therapeutic application. Researchers are responsible for compliance with all applicable regulations in their jurisdiction.
Identity & Purity
HPLC / MS-UPLC| Test | Specification | Result |
| Appearance | White lyophilised powder | ✓ Conforms |
| HPLC Purity | ≥ 99% | 99% ✓ |
| MS Molecular Weight | Expected ± 0.5 Da | Confirmed ✓ |
| Amino Acid Analysis | Theoretical sequence | Confirmed ✓ |
| Water Content (KF) | ≤ 8.0% | 5.4% ✓ |
| Net Peptide Content | ≥ 85.0% | 90.8% ✓ |
Safety Testing
Endotoxin / Metals| Test | Specification | Result |
| Endotoxin (LAL) | ≤ 5 EU/mg | 0.9 EU/mg ✓ |
| Bioburden | ≤ 100 CFU/g | <10 CFU/g ✓ |
| Lead (Pb) | ≤ 10 ppm | <0.1 ppm ✓ |
| Arsenic (As) | ≤ 5 ppm | <0.1 ppm ✓ |
| Mercury (Hg) | ≤ 3 ppm | <0.1 ppm ✓ |
| Cadmium (Cd) | ≤ 5 ppm | <0.1 ppm ✓ |
Solubility: Water / Acetic acid. Mix gently by rolling — do not vortex.
Returns: Sealed, unopened vials may be returned within 14 days of receipt. Opened vials cannot be returned.
Melanotan-2 is an artificial analog of the α-melanocyte-stimulating hormone (α-MSH) that is studied in experimental research due to its interaction with melanocortin receptors. The compound is provided only for experimental research use.
Yes. You can purchase Melanotan-2 online at PeptidesX for research use in the UK. It is supplied exclusively for research and is not intended for human and veterinary use.
Research peptides like Melanotan-2 can be purchased in the UK if supplied only for experimental research use. They are not medicinal products and must not be promoted or used for human consumption. Responsibility for the compliance of buyers with all necessary laws lies with the purchasers.
Navigate to the PeptidesX website, choose the necessary Melanotan-2 peptide, place it in your basket, and proceed to check out. All products are supplied under research-use-only conditions.
PeptidesX provides research peptides with analytical certificates per batch, where available. Researchers should consult the relevant Certificate of Analysis in terms of purity, identity, and batch of the product prior to conducting experiments in the laboratory.
Scientists study Melanotan-2 because it triggers melanocortin receptors, which enables research into melanogenesis, pigment control, neuroendocrine signalling, receptor pharmacology, and energy balance.
The following research areas in which Melanotan-2 is regularly studied include: - melanocyte biology and physiology, - pigmentation signaling pathways, - function of melanocortin receptors, - neuroendocrine signaling, - receptor binding properties, - cellular pharmacology.
Melanotan-2 is usually delivered in form of freeze-dried powder in an airtight laboratory research vial. For more information about product strengths, specifications and packaging refer to the appropriate product page on PeptidesX website.
Freeze-dried Melanotan-2 must be kept in a cool and dry place away from light. Usually, long-term storage requires refrigeration/freezing. After being dissolved it should be kept refrigerated and handled as per laboratory research protocol.
Yes. Researchers can study Melanotan-2 along with other melanocortin receptors agonists/antagonists as well as other peptides research chemicals in order to have a better understanding of receptor signaling processes and other biological mechanisms involved.
No. Melanotan-2 distributed by PeptidesX is meant to be used for laboratory research only. It is neither approved nor supplied for any human or veterinary applications.
No. PeptidesX provides Melanotan-2 solely for laboratory research use. It is neither marketed nor supplied for cosmetic/tanning and medical/personal use.
Delivery times vary depending on the delivery method chosen at checkout. Tracked delivery within the United Kingdom is offered by PeptidesX, with delivery times estimated at checkout.
Payment methods are listed at the checkout stage on the PeptidesX website. Payment methods may change from time to time, hence the need to consult the checkout page.
Melanotan-2 is meant for qualified researchers, universities, laboratories, research organizations, and scientific professionals for laboratory research purposes only. Buyers assure that the item will be used only for research purposes and not for human/animal use.