Retatrutide
Retatrutide (LY3437943) is a tripeptide agonist that works by activating GLP-1, GIP, and glucagon receptors at once. It is one of the most extensively studied metabolically acting peptides today, particularly in terms of its application to obesity studies.
About Retatrutide
Retatrutide is a long-acting triple receptor agonist that aims at acting on GLP-1 (glucagon-like peptide-1), GIP (glucose-dependent insulinotropic polypeptide), and glucagon receptors simultaneously. The ability to act through multiple receptor sites makes this an extremely useful research compound in metabolism studies.
It has been widely studied clinically and preclinically in the field of obesity, metabolic syndrome, non-alcoholic fatty liver disease (NAFLD), and cardiovascular risk factor modification. It is available exclusively for research purposes only.
Research Areas
- Triple GLP-1/GIP/glucagon receptor agonism and metabolic pathway research
- Obesity and adipose tissue regulation studies in animal models
- Insulin secretion and glucose homeostasis mechanism investigation
- Non-alcoholic fatty liver disease (NAFLD) research in controlled environments
- Cardiovascular risk factor modulation studies in laboratory settings
- Energy expenditure and thermogenesis pathway investigations
⚠ Research Use Only.
All products supplied by PeptidesX are intended strictly for in-vitro laboratory and scientific research. Not for human consumption, medical use, veterinary use, or therapeutic application. Researchers are responsible for compliance with all applicable regulations in their jurisdiction.
Identity & Purity
HPLC / MS-UPLC| Test | Specification | Result |
| Appearance | White lyophilised powder | ✓ Conforms |
| HPLC Purity | ≥ 98.0% | 99.1% ✓ |
| MS Molecular Weight | Expected ± 0.5 Da | Confirmed ✓ |
| Amino Acid Analysis | Theoretical sequence | Confirmed ✓ |
| Water Content (KF) | ≤ 8.0% | 5.4% ✓ |
| Net Peptide Content | ≥ 85.0% | 90.8% ✓ |
Safety Testing
Endotoxin / Metals| Test | Specification | Result |
| Endotoxin (LAL) | ≤ 5 EU/mg | 0.9 EU/mg ✓ |
| Bioburden | ≤ 100 CFU/g | <10 CFU/g ✓ |
| Lead (Pb) | ≤ 10 ppm | <0.1 ppm ✓ |
| Arsenic (As) | ≤ 5 ppm | <0.1 ppm ✓ |
| Mercury (Hg) | ≤ 3 ppm | <0.1 ppm ✓ |
| Cadmium (Cd) | ≤ 5 ppm | <0.1 ppm ✓ |
Solubility: Water / PBS. Mix gently by rolling — do not vortex.
Returns: Sealed, unopened vials may be returned within 14 days of receipt. Opened vials cannot be returned.
Retatrutide is a legally sold drug in the United Kingdom for the purpose of conducting laboratory and scientific researches. The compounds offered by PeptidesX should be used solely for in-vitro researches, according to the UK law. They should not be ingested.
Each order contains: lyophilized peptide in a vial, certificate of analysis per batch (confirmed through HPLC & MS), research usage label, and cold chain shipping.
Orders received prior to 3 PM on weekdays will be shipped out on the same day using Royal Mail Tracked 24 service. You will get your tracking number through an email. Delivery times in the UK are usually next-day.
Yes. We provide bulk discounts for labs, universities, and regular researchers. Please send us your specifications and we will provide you with a customized quotation.
All batches are separately tested by an ISO 17025 certified third-party lab using HPLC and MS-UPLC technologies. Our certificates are not self-certified – batch specific test reports are provided with each shipment, not generic PDFs.